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ICG-001, a preclinical agent, binding CBP and disrupting its interaction with -catenin, is efficacious killing tumour cells in both vitro experiments and mouse xenograft models of colon cancer and pancreatic ductal adenocarcinoma (PDAC)

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Its unique gastric stability distinguishes it from other regenerative peptides

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For example, it is not clear whether the gut microbiota can produce SFN-conjugates such as glutathione SFN-conjugate (SFN-GSH) or SFN-N-acetylcysteine conjugate (SFN-NAC) or identified compounds are produced by human cells

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